For a "full" installation of KB2533 on 64-bit systems, ensure that:
windows6.1-kb2533623-x64.msu
Extract the .cab file from the .msu using: Expand –F:* C:\path\to\Windows6.1-KB2533623-x64.msu C:\dest\folder\ windows update kb2533 64 bit full
Are you trying to install a that is giving you a missing prerequisite error? For a "full" installation of KB2533 on 64-bit